• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Guidance device for hepatic surgery, particularly applicable for use in radiofrequency ablation in open surgery and lost metastasis, configured from a housing (2), of suitable shape and size to fit over the liver of the patient, equipped with one or more cylinders (3) with an axial through hole (4) defining a guiding channel for the insertion of needles (5) of those used for radiofrequency ablation and lost metastasis, said casing (2) being with said cylinders (3) specifically designed, in its form and arrangement of the cylinders (3), for each particular case on the three-dimensional image obtained with computer processes, from anatomical information of the liver segmentation and the position of the needles, and generated by algorithms based on a previously performed diagnosis. It is manufactured by 3D printing with biocompatible and sterilizable material. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2719279A1
    申请号:ES201830023
    申请日:2018-01-09
    公开日:2019-07-09
    发明作者:Campos Ricardo Robles；Calderon Dario Garcia；Conesa Asuncion Lopez；Roberto Brusadin；Lopez Victor Lopez
    申请人:Cella Medical Solutions Sl；
    IPC主号:
    专利说明:

    [0001]
    [0002] GUIDANCE DEVICE FOR HEPATIC SURGERY
    [0003]
    [0004] OBJECT OF THE INVENTION
    [0005]
    [0006] The invention, as expressed in the statement of the present specification, refers to a guiding device for liver surgery, which provides structural and constitutive characteristics, which will be described in detail below, which represent a remarkable novelty for the current state. of the technique within its field of application.
    [0007]
    [0008] More particularly, the object of the invention is focused on a medical instrument whose design and manufacture are oriented to provide a guiding device in liver surgery interventions, specifically for radiofrequency ablation in open surgery and "missing metastasis" or "metastasis. lost ”, allowing to perform these actions avoiding vasculature, reducing intervention times and increasing the accuracy of the treatment, said device being formed by a housing equipped with orificed cylinders to guide the insertion of needles, specifically designed, both in shape and in the arrangement of said cylinders, for each particular case and obtained by 3D printing with biocompatible material.
    [0009]
    [0010] FIELD OF APPLICATION OF THE INVENTION
    [0011]
    [0012] The field of application of the present invention is part of the industry sector dedicated to the manufacture of medical devices, devices and accessories, focusing particularly on the scope of those applicable as an aid instrument in liver surgery.
    [0013]
    [0014] BACKGROUND OF THE INVENTION
    [0015]
    [0016] Radiofrequency ablation in the liver is a surgical treatment that destroys the tumor without removing it. During this procedure, the surgeon inserts, guided by intraoperative ultrasound, a thin needle-like probe into the tumor. Then a high frequency electric current is passed through the end of the probe, which heats the tumor and destroy cancer cells.
    [0017]
    [0018] In this treatment the surgeon must find the tumors by ultrasound to be able to insert the needle into them. Sometimes the tumors are not easily accessible, having to pass through the hepatic vasculature with the needle and, consequently, generating internal bleeding during the process.
    [0019]
    [0020] In addition to other injuries it is not possible to introduce the needle precisely, which affects the effectiveness of the treatment.
    [0021]
    [0022] There are also lesions in which the radiofrequency treatment is discarded, since it cannot be located well by ultrasound, or it consumes a lot of time its location.
    [0023]
    [0024] A first objective of the present invention is, therefore, to develop a guiding device that avoids said inconveniences and allows radiofrequency ablation to be avoided avoiding vasculature, reducing intervention times and increasing treatment accuracy.
    [0025]
    [0026] The concept of "lost metastasis", meanwhile, refers to a tumor lesion that before chemotherapy treatment (QT) could be seen by diagnostic imaging techniques, such as CT (computed tomography) or ultrasound, and yet after the treatment of QT they are not invisible due to their size (or other factors). During the surgery these lesions must be removed, presenting the inconvenience that they cannot be seen, therefore having to perform more extensive and therefore less safe and effective resections.
    [0027]
    [0028] A second objective of the invention is, therefore, the development of a guiding device that also allows to locate the lost metastases during the intervention, avoiding the vasculature and reducing the intervention times.
    [0029]
    [0030] On the other hand, and as a reference to the current state of the art, it should be noted that, at least by the applicant, the existence of any other guidance device for liver surgery, or any other invention of similar application, that presents some technical, structural and constitutive characteristics equal or similar to those presents the one claimed here.
    [0031]
    [0032] EXPLANATION OF THE INVENTION
    [0033]
    [0034] The guiding device for liver surgery that the invention proposes is thus configured as a novelty within its field of application, since in accordance with its implementation and in a restrictive manner the objectives indicated above are satisfactorily achieved, the characterizing details being they distinguish it, conveniently set out in the final claims that accompany the present description.
    [0035]
    [0036] Specifically, what the invention proposes, as noted above, is a guiding device applicable for use in two specific types of liver surgery that are radiofrequency ablation in open surgery and lost metastasis, which consists, essentially , in a housing equipped with orified cylinders to guide the insertion of needles, being specifically designed, in its shape and in the arrangement of the cylinders, for each particular case and obtained by 3D printing with biocompatible material.
    [0037]
    [0038] More specifically, the following is done to make the housing:
    [0039]
    [0040] - From the diagnosis by image (Computed Tomography or Nuclear Magnetic Resonance among others) of the patient's liver, and by means of specific algorithms for medical image processing, the following anatomical elements of the liver are selected (segmented): parenchyma, suprahepatic vein, vein portal, hepatic artery, bile duct and tumor. The segmentation of the medical image can also be carried out semi-automatically using specialized personnel.
    [0041]
    [0042] - Subsequently an algorithm is used to position in a three-dimensional image of the liver, reproduced by computer program from the previous diagnosis, the needles (injection in radiofrequency ablation and harpoon for lost metastases), based on avoiding vasculature, establishing the shorter distance between tumor and liver surface and define the needle position as anterior as possible to improve ergonomics in the posterior positioning of the guide carcass.
    [0043] - With the anatomical information of the segmentation and the position of the needles, the carcass is designed on the three-dimensional image obtained with at least one or more cylinders with through holes of suitable diameter to introduce, through each of them, The needle is a length determined according to the diagnosis made, said cylinders being arranged with the appropriate inclination in each case, since the holes determine the angle of entry of the needles.
    [0044]
    [0045] Preferably, the carcass is formed by two zones: the first is the fixation zone, the design of which is based on the angles of the segmented liver surface. The second is a projection of the fixation zone, called the needle positioning zone. In this area are the cylinders with holes mentioned above.
    [0046]
    [0047] If possible, the carcass is designed to position it on the left lobe of the liver. In this way the subsequent positioning on the patient's liver is easier. In cases where it is not possible, it is designed for the right lobe of the liver
    [0048]
    [0049] Additionally, the housing allows subsequent confirmation of the location of the lesion by ultrasound, for which, either it is configured so that it can be separated after inserting the needles, for example by having removable cylinders of the body of the housing itself, or it has a configuration that allows the ultrasound probe to be introduced, for example through a hole provided for that purpose in the body of the same.
    [0050]
    [0051] Logically, the diameter of the cylinders and their holes will be adequate to be able to choose the diameter of the needle in each case.
    [0052]
    [0053] The housing is designed, then, using specific modeling algorithms and, based on the design obtained, is made by 3D printing using biocompatible and sterilizable material.
    [0054]
    [0055] In view of the foregoing, it is found that the described guiding device for liver surgery represents an innovative structure with structural and constitutive characteristics unknown until now for the purpose to which it is intended, reasons that, together with its practical utility, provide it with a sufficient basis for get the privilege of exclusivity that is requested.
    [0056]
    [0057] DESCRIPTION OF THE DRAWINGS
    [0058]
    [0059] To complement the description that is being made and in order to help a better understanding of the characteristics of the invention, the present specification is attached, as an integral part thereof, of a plan, in which for illustrative purposes and not limiting the following has been represented:
    [0060]
    [0061] Figure number 1.- Shows a representation of the three-dimensional image that is used to design the device that constitutes the object of the invention, based on the diagnostic data obtained in each case, showing the anatomical elements of a liver and an example of housing design coupled to it, showing the arrangement of the needles in different orified cylinders.
    [0062]
    [0063] And figure number 2.- Shows a perspective view of a physical example of the housing that constitutes the guiding device for liver surgery, object of the invention, appreciating the parts and elements it comprises, as well as its configuration and arrangement.
    [0064]
    [0065] PREFERRED EMBODIMENT OF THE INVENTION
    [0066]
    [0067] In view of the aforementioned figures, and according to the numbering adopted, an example of a non-limiting embodiment of the guided liver surgery device can be seen, which comprises the parts and elements that are indicated and described in detail then.
    [0068]
    [0069] Thus, as seen in Figure 2, the device (1) in question is configured essentially from a housing (2), of shape and dimensions suitable for fitting on the patient's liver, which is provided with one or more cylinders (3) with an axial through hole (4) defining a guide channel for needle insertion (5) of those used in liver surgery for radiofrequency ablation in open surgery and for lost metastasis, said housing (2) with said cylinders (3) specifically designed, in its shape and arrangement of the cylinders, for each particular case on the three-dimensional image (A) obtained with computer processes, based on anatomical information on the segmentation of the liver and the position of the needles, and generated by algorithms based on a diagnosis made previously.
    [0070]
    [0071] Preferably, the housing (2) comprises two distinct zones: a fixing zone (2a), whose design adapts the angles of the liver surface of the patient in question; and a positioning zone (2b) of the needle (5), where the cylinders (3) with the through axial hole (4) mentioned above meet.
    [0072]
    [0073] In the preferred embodiment, and whenever possible, the housing (2) has a configuration that is adapted to position it on the left lobe of the liver. Although, alternatively, when the above is not possible, the configuration of the housing (2) is designed for adaptation on the right lobe of the liver.
    [0074]
    [0075] In any case, the device (1) allows confirmation of the location of the lesion by ultrasound during the intervention, for which, in an embodiment option the cylinders (3) are removable from the housing (2) allowing the separation of the same after introducing the needles (5), and, in an alternative or complementary option, the housing (2) has a gap (6) that allows the ultrasound probe to be inserted.
    [0076]
    [0077] Finally, it should be noted that the device (1), in any of its options, is preferably manufactured by 3D printing with biocompatible and sterilizable material.
    [0078]
    [0079] Figure 1 shows a schematic example of the three-dimensional image (A) that is generated to design the device (1), and which is constructed based on the information obtained with the previous diagnosis of liver segmentation, represented with a line dashed (h), to avoid vasculature, represented in a thin line (v), and to define the points (p) to attack and the angles at which the needles (5) must be inserted. Showing the design that must have the housing (2) and the areas of the same for fixing (2a) and positioning (2b) as well as the number and arrangement of the cylinders (3) to be presented.
    [0080]
    [0081] And in figure 2 the device (1) itself can be observed, once obtained by 3D printing from the above design, it being understood that the example represented in this Figure 2 does not correspond to the design shown in Figure 1, but it is a different example.
    [0082]
    [0083] Describing sufficiently the nature of the present invention, as well as the way of putting it into practice, it is not considered necessary to make its explanation more extensive so that any person skilled in the art understands its scope and the advantages that derive from it, stating that, within its essentiality, it may be carried out in other embodiments that differ in detail from that indicated by way of example, and to which it will also achieve the protection that is sought provided that it does not alter, change or modify its fundamental principle .
    权利要求:
    Claims (7)
    [1]
    1. - GUIDING DEVICE FOR HEPATIC SURGERY which, particularly applicable for use in radiofrequency ablation in open surgery and lost metastasis, is characterized by being configured from a housing (2), of suitable shape and dimensions to fit over the patient's liver, equipped with one or more cylinders (3) with a through axial hole (4) that defines a guide channel for the insertion of needles (5) from those used for radiofrequency ablation and lost metastasis, said housing (2) with said cylinders (3) specifically designed, in its shape and arrangement of the cylinders (3), for each particular case on the three-dimensional image (A) obtained with computer processes, from anatomical information of the segmentation of the liver and needle position, and generated by algorithms based on a diagnosis made previously.
    [2]
    2. - GUIDING DEVICE FOR HEPATIC SURGERY, according to claim 1, characterized in that the housing (2) comprises two distinct zones: a fixing zone (2a), whose design adapts the angles of the liver surface of the patient in question ; and a positioning zone (2b) of the needle (5), where the cylinders (3) are located with the axial through hole (4).
    [3]
    3. - GUIDING DEVICE FOR HEPATIC SURGERY, according to claim 1 or 2, characterized in that the housing (2) has a configuration that is adapted to position it on the left lobe of the liver.
    [4]
    4. - GUIDING DEVICE FOR HEPATIC SURGERY, according to claim 1 or 2, characterized in that the housing (2) has a configuration that is adapted to position it on the right lobe of the liver.
    [5]
    5. - GUIDING DEVICE FOR HEPATIC SURGERY, according to any of claims 1 to 4, characterized in that the cylinders (3) are removable from the housing (2) allowing separation thereof after inserting the needles (5) , for example in order to confirm the location of the ultrasound lesion during the intervention.
    [6]
    6. GUIDING DEVICE FOR HEPATIC SURGERY, according to any of claims 1 to 5, characterized in that the housing (2) has a recess (6) that allows the introduction of an ultrasound probe.
    [7]
    7. GUIDING DEVICE FOR HEPATIC SURGERY, according to any of claims 1 to 6, characterized in that it is manufactured by 3D printing with biocompatible and sterilizable material.
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    引用文献:
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    法律状态:
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